Students Committees 2021/22

In October 2021 College students elected a new, 6 member strong executive of the Volta Students' Union (3 undergraduates and 3 postgraduates).  No election had taken place in October 2020 due to Covid restrictions. The turnout in October 2021 was low (36.7%).  Elected committee members are listed below.


Volta Students' Union Executive


Name: Francesco Zambrini (President)
Course: Medicine, Year 2
Roles:

Name: Angelica Scarpellini
Course: Medicine, Year 2
Reoles:

Name: Nicola Loizzo
Course: Medicine, Year 2
Roles:

 

Name: Annalisa Barone
Course: Physical Education, Year 1 (MSc)
Roles:

Name: Mircea A Codrea
Course: Physics, Year 2 (MSc)
Roles:

Name: Andrea Caiulo
Course: Computer Science, Year 2 (MSc)
Roles:

 

 

Saturday, 16 October 2021 12:19

VSU Committee

The new Volta Students Union (VSU) Committee (Comitato Alunni in EDiSU vocabulary) will be elected on Tuesday 19th of October. 

A poster listing the candidates and summarising the procedure is available here.

In the afternoon of Monday 18th October at 6.00 pm the candidates will introduce themselves to a General Students Assembly in the College Lecture Theatre and will discuss with members of the College their ideas and plans for College development. Actual voting will take place on Tuesday 19th from 8.00 am to 6.00 pm. The list of students entitled to vote and the ballot boxes will be located at the porter's desk.  Undergraduate students will elect three undergraduate representatives, postgraduate students will elect three postgraduate representatives. Each student votes a one representative.  The list of candidates is provided below as well. 

Undergraduates
N Loizzo, Medicine yr 2,
A Scarpellini, Medicine yr 2,
EA Perli, Mathematics yr 2,
F Zambrini, Medicine yr 2.

Postgraduates
OD Adeniyi, Environmental Science, yr 2 (PhD),
A Barone, Physical Education, yr 1 (MSc),
A Caiulo, Computer Science, yr 2 (MSc),
P Catarsi, Bioengineering yr 3 (PhD),
MA Codrea, Physics, yr 2 (MSc)

Students representation and contribution to College life and development are taken in the highest regard at Volta and all College members are strongly invited to participate in the election and cast their vote.








Saturday, 16 October 2021 09:42

Mechanosensing

Giancarlo Forte of the International Clinical Research Center, St. Anne’s University, Brno, Czech Republic and University of Turku, Finland will give a talk at 5.00 pm on the 18th of October on Understanding cell-matrix interaction and mechanosensing to counteract diseases. The talk will be available online at the following link:

https://us02web.zoom.us/meeting/register/tZAqduGhqz0pGdNm1rjHhecNtpkxJnqu_RrM

The seminar poster that can be downloaded here. Further information about the seminar including the abstract and a biographical sketch of the speaker can be found at this page.  All College students are invited to attend, especially undergraduates and postgraduates reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine and PhD students engaged in research projects in the biomedical area.

Image: immunofluorescent staining of microtubules (red) and actin (green).






Understanding cell-matrix interaction and mechanosensing to counteract diseases

18th October 2021.  Giancarlo Forte, St. Anne’s University, Brno, Czech Republic and University of Turku, Finland

Understanding cell-matrix interaction and mechanosensing to counteract diseases.

Giancarlo Forte of the International Clinical Research Center, St. Anne’s University, Brno, Czech Republic and University of Turku, Finland will give a talk at 5.00 pm on the 18th of October on Understanding cell-matrix interaction and mechanosensing to counteract diseases. The talk will be available online at the following link:

https://us02web.zoom.us/meeting/register/tZAqduGhqz0pGdNm1rjHhecNtpkxJnqu_RrM

The seminar poster that can be downloaded here. All College students are invited to attend, especially undergraduates and postgraduates reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine and PhD students engaged in research projects in the biomedical area.

Abstract
Downstream of ECM remodelling, the aberrant activation of the mechanosensing apparatus contributes to the establishment and progression of age-related pathologies, like cancer and cardiovascular diseases. My group is interested in understanding how ECM remodelling determines opposite consequences in rather different biological systems, like tumors and the heart. In particular, we focus on dissecting the molecular mechanisms controlling the divergent response to mechanical stress of cardiomyocytes - which are induced to hypertrophy - and cancer cells - which tend to proliferate and disseminate. Mechanosensitive proteins have been recently identified that respond to ECM pathological remodelling and trigger the growth and dissemination of different tumor types. Our group demonstrated how ECM pathological remodelling determines changes in the assembly of focal adhesions through the mechanical control of Yes Associated Protein (YAP) in breast cancer. We also described how YAP aberrant activation contributes to cardiac ECM pathological remodelling in heart failure. In this context, we recently identified RNA binding protein hnRNPC conferring mRNA metabolism sensitivity to cardiac ECM mechanical turmoil and impinging on the alternative splicing of components of mechanosensitive pathways.  In the presentation, I will describe our strategy to disentangle the contribution of pathological mechanosensing to hyperplastic and hypertrophic phenotypes and will briefly discuss how we plan to exploit 3D complex disease models based on induced pluripotent stem cells (iPSCs), and tumor spheroids derived from patients or cell lines to answer our scientific questions.

Biography
The speaker is Deputy Director for Science of the International Clinical Research Center, an Institute of excellence funded by European Union within St. Anne’s University Hospital in Brno, Czech Republic (FNUSA-ICRC).  He also serves as Group Leader of the Center for Translational Medicine (CTM) at FNUSA-ICRC and holds an Adjunct Professor position in Cell Biology and Biomaterials at the University of Turku (Finland). Dr. Forte obtained his Master Degree in Cellular and Molecular Biology in 2000 at the University of Rome Tor Vergata (Italy), where he also completed his PhD in 2005 in Experimental Pathophysiology.

Image
Computer image of a fibrin network. Courtesy of Farzan Beroz, Princeton University.

 

 

Thursday, 14 October 2021 09:14

The p53 tumour suppressor

On the 15th of October Roger Leng of the University of Alberta, Canada will give a talk at 5.00 pm on The p53 Pathway in Cancer and Potential Therapeutic Applications. The talk will be available online at the following link:
https://us02web.zoom.us/meeting/register/tZAvd-6rqDsiHdLi_lePKKy1lhKBQW7VY8DB

The product of the p53 gene is a transcription factor with crucial tumour suppressor functions. Mutations in the p53 gene occur very frequently in human cancers and contribute to tumour onset and/or progression.  The seminar will discuss research the role of p53 in cancer and new approaches to restore p53 activity in cells that have lost it.

The seminar poster that can be downloaded here. Further details, including a seminar abstract and a biographical sketch of the speaker are available at this page.  All College students are invited to attend, especially undergraduates and posgraduates reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine and PhD students incolved in life science projects.

Image: immunofluorescent staining of human cells for p53 (green) and actin (red).






The p53 Pathway in Cancer and Potential Therapeutic Applications

15th October 2021.  Roger Leng, University of Alberta, Canada

The p53 Pathway in Cancer and Potential Therapeutic Applications

Roger Leng of the University of Alberta, Canada will give a talk at 5.00 pm on the 15th of October on The p53 Pathway in Cancer and Potential Therapeutic Applications. The talk will be available online at the following link:

https://us02web.zoom.us/meeting/register/tZAvd-6rqDsiHdLi_lePKKy1lhKBQW7VY8DB

The seminar poster that can be downloaded here. All College students are invited to attend, especially undergraduates and postgraduates reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine and PhD students engaged in research projects in the biomedical area.

Abstract
The seminar will offer background information about the p53 and ubiquitin-proteasome pathways and will next cover the speaker's own research on p53-tumors and the regulation of the activity of members of p53 protein members inside the cells regulation. Finally the seminar will offer an outline of the author's future programmes of research in the p53 field.

Image
Brown/black staining of prostate cancer cells with an anti-p53 antibody (PreproTech) demonstrates the predominat nuclear localisation of the protein (darker staining).

 

 

Wednesday, 13 October 2021 06:38

The CCR5 Receptor

On the 13th of October Luca Vangelista of the University of Nazarbayev, Kazakhstan will give a talk at 5.00 pm on CCR5: a Crossroad for Infection and Inflammation. The talk will be available online at the following link:
https://us02web.zoom.us/j/88600327505?pwd=TDZLYlBoYTgzcmNIMXI3UlZ5dy94Zz09


The CCR5 receptor plays a key role in the entrance of HIV in target cells. HIV is the virus causing the Acquired Immuno Deficienty Syndrome (AIDS), a disease that has killed over 36 million people from 1981 to 2020.  The seminar will discuss research on CCR5 in the context of the HIV infection as well as other roles of this receptor in inflammation. 

The seminar poster that can be downloaded here. Further details, including a seminar abstract and a biographical sketch of the speaker are available at this page.   All College students are invited to attend, especially undergraduates and posgraduates reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine and PhD students incolved in life science projects.

Image: an electron micrograph of the HIV virus (courtesy of H Gelderblom, Robert Koch Institute, Berlin).






CCR5: a Crossroad for Infection and Inflammation

13th October 2021.  Luca Vangelista, University of Nazarbayev, Kazakhstan

CCR5: a Crossroad for Infection and Inflammation

Luca Vangelists of the University of Nazarbayev, Kazakhstan will give a talk at 5.00 pm on the 13th of October on CCR5: a Crossroad for Infection and Inflammation. The talk will be available online at the following link:

https://us02web.zoom.us/j/88600327505?pwd=TDZLYlBoYTgzcmNIMXI3UlZ5dy94Zz09

The seminar poster that can be downloaded here. All College students are invited to attend, especially those reading Biology, Biotechnology, Pharmaceutical Sciences and Medicine.

Abstract
CCR5 and its interaction with chemokine ligands have been crucial for understanding and tackling HIV-1 entry into target cells. Over time, CCR5 was found to be central in a growing number of pathophysiological conditions. Expressed on various cell types, CCR5 plays a pivotal role in the inflammatory response by directing cells to sites of inflammation, ultimately resulting in major diseases such as cancer and atherosclerosis. Many infectious agents use CCR5 either by a direct interaction with the receptor during their pathogenesis (e.g., HIV-1 and S. aureus) or by indirect strategies exploiting receptor activation. The massive efforts devoted to combat HIV-1 entry by interfering with CCR5, and the subsequent production of chemokine ligand variants, small chemical compounds, and other molecular entities and strategies, may set the therapeutic standards for a wealth of different pathologies.

Biography
- Degree in Chemistry and Pharmaceutical Technology at the University of Padova, Italy.
- PhD in Molecular Biology at the University of Heidelberg, Germany, for the PhD work at the Structural Biology Program of the European Molecular Biology Laboratory (EMBL) headquarters in Heidelberg.
- Postdoctoral Fellow in the Molecular Immunology Group at the International Centre for Genetic Engineering and Biotechnology in Trieste, Italy.
- Research Scientist at the San Raffaele Scientific Institute and the University of Milan, Italy.
- Group Leader (Protein Engineering and Therapeutics) at the San Raffaele Scientific Institute, Milan, Italy.
- Associate Professor & Director Master in Molecular Medicine at the Nazarbayev University School of Medicine, Nur-Sultan (Astana), Kazakhstan.
- Visiting Scientist at GSK (UK), University of Vienna (Austria), Sanquin Research Amsterdam (Netherland), Biozentrum Basel (Switzerland) and Osel Inc. (USA).

Image
The structure of a CCR5 peptide involved in the interaction with the HIV gp120 protein (pdb code: 2l87)

 

 

Volta Debating Society (VDES)

Debate is the the cornerstone of democratic culture and a quintessential feature of University life. There is tradition of formal University-based debates in a number of Institutions in the English-speaking world and, following in this tradition, Volta has promoted its own Volta Debating Society with the aim to offer students basic debating skills, foster internal debate on major topics and encourage an inter-collegiate debating context. The style of these debates will follow that of British Parliamentary debates and the ultimate aim of these activities is to assemble a University-wide team that will represent the University of Pavia at the annual World Universities Debating Championship  due to take place in Belgrade in 2022 and in Madrid in 2023. 

The College is grateful to Arianna Armanetti (Physics, year 3) for advocating the debating culture inside Volta, for providing a basic course of debating sklls in the academic year 2020/21and for acting as the first secretary to the Volta Debating Society for the academic years 2020/21 and 2021/22.  The following College students were the the first members of tthe VDES: Federico Bertelli, Giulia Bonasegale, Raffaele Castellucci, Andrea Cerbone, Mircea Codrea, Davide Gianatti, Giacomo Maggiorano, Chiara Mogliazza, Alessandra Ria and Marco Silvestri. 
Internal and inter-collegiate debating events will be reported in the News & Events section of the College web site. Details of the 2021/22 'The Art and Tehnique of Debating' Course will be published alongside the details of other College Courses (personale development, language, computing, etc) in the earlier part of the 2021/22 academic year.

Image: a debate of the Cambridge Union, the oldest known University Debating Society (founded 1815).

Saturday, 24 April 2021 18:55

Entrepreunership Club - Pavia

Elisa Seghetti, a member of Collegio Nuovo and co-founder of Entrepreneurship Club Pavia (E-Club Pavia for short) is bringing E-Club Pavia to the attention of Volta students and is inviting members of Volta them to the next Club event.

E-Club Pavia is a University group aiming to create a network of University students with a serious interest in entrepreneurship and is organising a meeting online on Thursday, the 29th of April at 7.30 pm in collaboration with the startup Thesis4U and the student group ImGestionale during which 4 startup companies will outline their ideas and business plans and will illustrate in the process how to 'pitch' such presentations.

Business inclined members of Collegio A Volta are welcome to join the E-Club Pavia event on Thursday 29th at the following url  https://thesisforyou.com/iscriviti-allevento-su-come-fare-il-pitch/.

The College expresses its gratitude to Elisa Seghetti for extending this invitation to the members of Volta.



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